Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 6/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.41 |
| ▸ | SKP1 | P63208 | 1/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750251 | 0.80 | ATR (0.54) | ATRADORA2AADORA1HTTLMNA | |
| SCHEMBL19820819 | 0.77 | CKS1B (0.57) | ATRADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL13137930 | 0.76 | ATR (1.00) | ATR | |
| SCHEMBL6972758 | 0.76 | GABRA1 (0.51) | ATRGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31273715 | 0.76 | GABRG2 (0.50) | ATRGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL31663536 | 0.76 | GABRG2 (0.50) | ATRGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL28148511 | 0.76 | ALDH1A1 (0.51) | ATRGABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16750238 | 0.76 | CKS1B (0.49) | ATRPRKDCATMKDRALDH1A1 | |
| SCHEMBL87574 | 0.75 | CKS1B (0.55) | ATRKDRALDH1A1KDM4ECKS1B | |
| SCHEMBL385924 | 0.74 | ATR (0.62) | ATRGABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329903-B2 | Light-emitting element including organometallic complex including pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20120123117-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-05-17 | — | — | US | disclosed |
| US-8101755-B2 | Organometallic complex including pyrazine derivative | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20100105902-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105902-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | CRY1, CRY2, LAGE3 | ATR 2192/4885GABRG2 2846/4885GABRB3 4162/4885 |
| US-20120123117-A1 | Organometallic Complex, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Including the Organometallic Complex | CRY1, CRY2, LAGE3 | ATR 2192/4885GABRG2 2846/4885GABRB3 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.