Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTSV | O60911 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990972 | 0.79 | NR4A2 (0.48) | POLBKDM4EALDH1A1NPSR1HPGD | |
| SCHEMBL5100689 | 0.77 | GABRA1 (0.53) | TRPM8MAOAMAOBGABRA1GABRG2 | |
| SCHEMBL8637415 | 0.75 | KDM4E (0.55) | TRPM8MAOAMAOBGABRA1GABRG2 | |
| SCHEMBL6098744 | 0.75 | ALDH1A1 (0.57) | TRPM8POLBKDM4EALDH1A1MAPT | |
| SCHEMBL22074470 | 0.74 | TRPM8 (0.54) | TRPM8MAOAMAOBGABRA1GABRG2 | |
| SCHEMBL3389079 | 0.74 | TRPM8 (0.61) | TRPM8MAOAMAOBGABRA1GABRG2 | |
| SCHEMBL2084401 | 0.73 | MDH2 (0.66) | TRPM8POLBALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL25904016 | 0.73 | TRPM8 (0.59) | TRPM8MAOAMAOBGABRA1GABRG2 | |
| SCHEMBL8136752 | 0.72 | GABRA1 (0.63) | TRPM8GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL13344651 | 0.72 | NR4A2 (0.45) | POLBKDM4EALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283836-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | Aegera Therapeutics Inc. (CA) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001087887-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | AEGERA THERAPEUTICS INC. (CA) | 2001-11-22 | — | — | WO | disclosed |