Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.44 |
| ▸ | F10 | P00742 | 5/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979635 | 0.86 | ITGB3 (0.40) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL6978680 | 0.83 | KEAP1 (0.47) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL6982168 | 0.81 | F10 (0.42) | F2F10PRSS1 | |
| SCHEMBL7407619 | 0.80 | MAPT (0.34) | — | |
| SCHEMBL6976368 | 0.79 | ITGB3 (0.39) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL6981750 | 0.78 | AVPR2 (0.38) | F2F10PRSS1ITGB3ITGA2B | |
| SCHEMBL6982234 | 0.77 | TP53 (0.41) | F2F10PRSS1 | |
| SCHEMBL6982999 | 0.77 | ALDH1A1 (0.41) | F2PRSS1ITGB3ITGA2B | |
| SCHEMBL6976662 | 0.77 | F2 (0.60) | F2 | |
| SCHEMBL7084264 | 0.75 | F2 (0.40) | F2F10PRSS1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |