Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7767316 | 0.87 | L3MBTL1 (0.66) | L3MBTL1MAPTMEN1KMT2AGRIN2B | |
| SCHEMBL6983635 | 0.82 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1LMNASMN1; SMN2PLAAT3 | |
| SCHEMBL6983189 | 0.79 | GRIN2B (0.50) | MEN1KMT2AGRIN2BALDH1A1SMN1; SMN2 | |
| SCHEMBL6986510 | 0.78 | RAB9A (0.67) | L3MBTL1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3078714 | 0.76 | L3MBTL1 (0.68) | L3MBTL1MAPTMEN1KMT2AHTT | |
| SCHEMBL11223785 | 0.75 | L3MBTL1 (0.70) | L3MBTL1MAPTMEN1KMT2AHTT | |
| SCHEMBL199869 | 0.72 | L3MBTL1 (1.00) | L3MBTL1MAPTHTTALDH1A1LMNA | |
| SCHEMBL4066365 | 0.72 | MAPT (0.61) | L3MBTL1MAPTMEN1KMT2AGRIN2B | |
| SCHEMBL28552018 | 0.72 | L3MBTL1 (0.61) | L3MBTL1MAPTMEN1KMT2AGRIN2B | |
| SCHEMBL5680205 | 0.71 | L3MBTL1 (0.57) | L3MBTL1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | disclosed |