Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361527 | 0.81 | NPC1 (0.73) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL631022 | 0.81 | LTA4H (0.57) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL1304210 | 0.80 | NPC1 (1.00) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL6983635 | 0.78 | ALDH1A1 (0.53) | RAB9ANPC1ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL6985463 | 0.78 | L3MBTL1 (0.56) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL9595063 | 0.78 | PLAU (0.58) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL28267555 | 0.77 | TDP1 (0.69) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL24800806 | 0.75 | F2RL1 (0.74) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL248073 | 0.75 | NPC1 (0.73) | RAB9ANPC1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL11729686 | 0.75 | RAB9A (0.55) | RAB9ANPC1MAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294695-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | Ortho-McNeil Pharmaceutical, Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001085694-A2 | SUBSTITUTED DIAMIDE DERIVATIVES USEFUL AS MOTILIN ANTAGONISTS | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-11-15 | — | — | WO | disclosed |