Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CTSA | P10619 | 3/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698559 | 1.00 | LMNA (0.36) | LMNACTSAGABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL20703669 | 0.97 | LMNA (0.35) | LMNACTSAGABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL20703671 | 0.97 | LMNA (0.35) | LMNACTSAGABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL28402656 | 0.97 | LMNA (0.35) | LMNACTSAGABRA1GABRG2GABRB3 | |
| SCHEMBL25647101 | 0.97 | LMNA (0.36) | LMNACTSAGABRA1GABRG2GABRB3 | |
| SCHEMBL20703670 | 0.96 | LMNA (0.34) | LMNACTSA | |
| SCHEMBL18543889 | 0.90 | GABRA1 (0.36) | LMNACTSAGABRA1GABRG2GABRB3 | |
| SCHEMBL6906013 | 0.90 | GABRA1 (0.36) | LMNACTSAGABRA1GABRG2GABRB3 | |
| SCHEMBL1776465 | 0.89 | GABRA1 (0.37) | LMNACTSAGABRA1GABRG2GABRB3 | |
| SCHEMBL1776466 | 0.89 | GABRA1 (0.37) | LMNACTSAGABRA1GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971577-B1 | Process for the preparation of unsymmetric bis(imino) compounds | BASELL POLYOLEFINE GMBH (DE) | 2014-11-26 | — | — | EP | disclosed |
| US-8252875-B2 | Process for the preparation of unsymmetric bis(imino) compounds | BASELL POLYOLEFINE GMBH (DE) | 2012-08-28 | — | — | US | disclosed |
| EP-2423193-A1 | Process for preparing imino compounds | Basell Polyolefine GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-7795441-B2 | Process for preparing imino compounds | BASELL POLYOLEFINE GMBH (DE) | 2010-09-14 | — | — | US | disclosed |
| US-20090054609-A1 | Process for the Preparation of Unsymmetric Bis(Imino) Compounds | BASELL POLYOLEFINE GMBH (DE) | 2009-02-26 | — | — | US | disclosed |
| US-20090005571-A1 | Process for Preparing Imino Compounds | BASELL POLYOLEFINE GMBH (DE) | 2009-01-01 | — | — | US | disclosed |
| EP-1971577-A2 | PROCESS FOR THE PREPARATION OF UNSYMMETRIC BIS(IMINO) COMPOUNDS | Basell Polyolefine GmbH (DE) | 2008-09-24 | — | — | EP | disclosed |
| WO-2007080081-A2 | PROCESS FOR THE PREPARATION OF UNSYMMETRIC BIS(IMINO) COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2007-07-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005571-A1 | Process for Preparing Imino Compounds | MACO1, C9, PMS2 | LMNA 80/4885CTSA 4064/4885GABRA1 3663/4885 |
| US-20090054609-A1 | Process for the Preparation of Unsymmetric Bis(Imino) Compounds | FHIT, OAT, NONO | LMNA 2085/4885CTSA 4726/4885GABRA1 2764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.