Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6993029 | 0.93 | ALDH1A1 (0.48) | KMT2ACYP3A4ALDH1A1MEN1CYP1A2 | |
| SCHEMBL6990114 | 0.85 | LPAR1 (0.49) | KMT2ACYP3A4ALDH1A1MEN1LMNA | |
| SCHEMBL6986949 | 0.82 | SLC2A1 (0.48) | AOC3 | |
| SCHEMBL6239726 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPK1CA12CA1 | |
| SCHEMBL6985934 | 0.81 | MAPT (0.43) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6235518 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP1A2LMNAKDM4ECA12 | |
| SCHEMBL6990109 | 0.79 | LPAR1 (0.53) | KMT2ACYP3A4ALDH1A1MEN1KDM4E | |
| SCHEMBL6989792 | 0.78 | MEN1 (0.45) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL6989317 | 0.77 | SMN1; SMN2 (0.47) | CYP3A4CYP2D6LMNASMN1; SMN2CA1 | |
| SCHEMBL18864231 | 0.77 | MAPT (0.46) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |