Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14410355 | 0.82 | EGFR (0.38) | NOS3TAAR1NFKB1NOS2KDM4E | |
| SCHEMBL7939474 | 0.72 | TAAR1 (0.38) | NOS3TAAR1CYP1A2CYP3A4PKM | |
| SCHEMBL6981645 | 0.72 | TRPV3 (0.36) | CYP1A2ALDH1A1KCNH2 | |
| SCHEMBL4142328 | 0.72 | NOS3 (0.40) | NOS3TAAR1CYP1A2CYP3A4PKM | |
| SCHEMBL5218292 | 0.72 | NOS3 (0.40) | NOS3TAAR1CYP1A2CYP3A4PKM | |
| SCHEMBL5737404 | 0.72 | TAAR1 (0.54) | NOS3TAAR1ALDH1A1LMNANPC1 | |
| SCHEMBL8063119 | 0.69 | NOS3 (0.35) | NOS3NOS2RAB9AMAPT | |
| SCHEMBL14457975 | 0.69 | NOS3 (0.37) | NOS3TAAR1CYP1A2CYP3A4PKM | |
| SCHEMBL8789519 | 0.69 | TAAR1 (0.40) | NOS3TAAR1NOS2ALDH1A1NPC1 | |
| SCHEMBL8626888 | 0.68 | KDM1A (0.33) | NOS3TAAR1NOS2KDM4EKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6670307-B2 | Such as 2-(2,6-difluorophenyl)-4-(4-(2-ethoxypyridin-5-yl) phenyl)oxazoline; for administration to livestock | HOECHST SCHERING AGREVO GMBH (DE) | 2003-12-30 | — | — | US | disclosed |
| EP-1087967-B1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE GMBH (DE) | 2003-10-22 | — | — | EP | disclosed |
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | BAYER CROPSCIENCE AG (DE) | 2002-06-06 | — | — | US | disclosed |
| US-6265350-B1 | CONTROLLING HARMFUL FUNGI, INSECTS, ACARINA, MOLLUSKS AND NEMATODES | HOECHST SCHERING AGREVO GMBH (DE) | 2001-07-24 | — | — | US | disclosed |
| EP-1087967-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | Aventis CropScience GmbH (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065901-A1 | 1,3-OXAZOLINE AND 1,3-THIAZOLINE DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS PESTICIDES | AVENTIS CROPSCIENCE GMBH (DE) | 1999-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068828-A1 | 1,3-oxazoline and 1,3-thiazoline derivatives, their preparation, and their use as pesticides | MT-CO1, OXA1L, MT-CO3 | NOS3 454/4885TAAR1 628/4885CYP1A2 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.