Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987326 | 0.84 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL6989757 | 0.84 | MAPT (0.47) | ALDH1A1MAPTL3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL6985789 | 0.82 | HDAC1 (0.51) | ALDH1A1MAPTL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL6235626 | 0.82 | GPBAR1 (0.47) | ALDH1A1MAPTL3MBTL1KDM4CKDM5B | |
| SCHEMBL6988723 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1MAPTRAF1MAP2K1CYP1A2 | |
| SCHEMBL5210605 | 0.80 | CFTR (0.55) | ALDH1A1MAPTL3MBTL1KDM4CKDM5B | |
| SCHEMBL6991899 | 0.78 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1TP53KDM4C | |
| SCHEMBL6236957 | 0.77 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1SMN1; SMN2KDM4C | |
| SCHEMBL6235628 | 0.75 | KDM4C (0.48) | ALDH1A1MAPTKDM4CKDM5BKDM5A | |
| SCHEMBL6985787 | 0.74 | KDM4A (0.50) | ALDH1A1MAPTCYP1A2CYP2C19KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |