Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986161 | 0.87 | HTR1A (0.53) | HTR1AHTR7 | |
| SCHEMBL9266055 | 0.86 | HTR1A (0.54) | HTR1AHTR7 | |
| SCHEMBL9040830 | 0.85 | KCNH2 (0.52) | CCR3 | |
| SCHEMBL6988888 | 0.85 | DRD2 (0.57) | — | |
| SCHEMBL6991322 | 0.83 | SIGMAR1 (0.51) | — | |
| SCHEMBL9039006 | 0.83 | SIGMAR1 (0.47) | HTR1AHTR7 | |
| SCHEMBL9266205 | 0.82 | ALDH1A1 (0.45) | HTR1A | |
| SCHEMBL9266212 | 0.82 | ALDH1A1 (0.45) | HTR1A | |
| SCHEMBL6989707 | 0.81 | DRD3 (0.53) | HTR1AHTR7 | |
| SCHEMBL6984315 | 0.81 | HTR1A (0.49) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551527-B1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-5397780-A | Antiserotonine, hypotensive, congestive heart failure | SUNTORY LIMITED (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0551527-A1 | PYRROLOAZEPINE DERIVATIVE | SUNTORY LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |