Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995726 | 0.81 | HTR1D (0.48) | MEN1KMT2AMAPTALDH1A1THRB | |
| SCHEMBL6630124 | 0.81 | HTR1A (0.38) | HTR6MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6811873 | 0.80 | HTR6 (0.39) | HTR6MEN1KMT2AALDH1A1THRB | |
| SCHEMBL6995396 | 0.79 | HTR1D (0.51) | MEN1KMT2AMAPTALDH1A1THRB | |
| SCHEMBL6917704 | 0.70 | HTT (0.41) | MAPTALDH1A1DRD2DRD4HTT | |
| SCHEMBL6812183 | 0.69 | HTT (0.38) | ALDH1A1THRBDRD2DRD4CA1 | |
| SCHEMBL6808621 | 0.69 | HTR2C (0.39) | HTR6ALDH1A1DRD2DRD4CA1 | |
| SCHEMBL20718641 | 0.67 | MAPT (0.41) | MAPTALDH1A1THRBDRD2HTT | |
| SCHEMBL13197463 | 0.65 | ALDH1A1 (0.51) | MEN1KMT2AMAPTALDH1A1THRB | |
| SCHEMBL6811100 | 0.65 | CA7 (0.48) | HTR6DRD2DRD4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345930-A2 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050067-A2 | PHARMACEUTICAL HETEROCYCLIC COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-06-27 | — | — | WO | disclosed |