Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | RAF1 | P04049 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767102 | 0.83 | KDM4E (0.39) | KDM4ECYP3A4MAPTALOX15HPGD | |
| SCHEMBL17626333 | 0.81 | SMN1; SMN2 (0.49) | KDM4EMAPTHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL11166709 | 0.80 | NPY5R (0.45) | KDM4EALOX15SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1922247 | 0.77 | KDM4E (0.35) | KDM4ECYP3A4MAPTALOX15HPGD | |
| SCHEMBL557663 | 0.77 | KDM4E (0.41) | KDM4ECYP3A4MAPTHPGDALDH1A1 | |
| SCHEMBL1902062 | 0.77 | ALOX15 (0.41) | KDM4ECYP3A4MAPTALOX15HPGD | |
| SCHEMBL5187331 | 0.76 | AURKA (0.44) | KDM4ECYP3A4MAPTSMN1; SMN2NPC1 | |
| SCHEMBL4522594 | 0.76 | KDM4E (0.33) | KDM4ECYP3A4MAPTALOX15HPGD | |
| SCHEMBL18129429 | 0.75 | NPC1 (0.58) | KDM4ECYP3A4MAPTALOX15HPGD | |
| SCHEMBL11222851 | 0.72 | MAPT (0.39) | KDM4EMAPTHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11947259-B2 | Photoinitiator composition containing acylcarbazole derivative and carbazolyl oxime ester, and use thereof in photocurable composition | IGM (ANQING) HIGH TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2024-04-02 | — | — | US | claimed |
| US-20220185775-A1 | NOVEL DIAROYL CARBAZOLE COMPOUND AND USE THEREOF AS SENSITISING AGENT | IGM (Anqing) High Technology Development Co., Ltd. (CN) | 2022-06-16 | — | — | US | claimed |
| US-20220179309-A1 | PHOTOINITIATOR COMPOSITION CONTAINING ACYLCARBAZOLE DERIVATIVE AND CARBAZOLYL OXIME ESTER, AND USE THEREOF IN PHOTOCURABLE COMPOSITION | IGM (ANQING) HIGH TECHNOLOGY DEVELOPMENT CO., LTD (CN) | 2022-06-09 | — | — | US | claimed |
| CN-113518774-A | Novel diarylacylcarbazole compound and application thereof as sensitizer | 艾坚蒙(安庆)科技发展有限公司 | 2021-10-19 | — | — | CN | claimed |
| WO-2020253283-A1 | NOVEL DIAROYL CARBAZOLE COMPOUND AND USE THEREOF AS SENSITISING AGENT | 江苏英力科技发展有限公司 | 2020-12-24 | — | — | WO | claimed |
| WO-2020253284-A1 | PHOTOINITIATOR COMPOSITION CONTAINING ACYLCARBAZOLE DERIVATIVE AND CARBAZOLYL OXIME ESTER, AND USE THEREOF IN PHOTOCURABLE COMPOSITION | 江苏英力科技发展有限公司 | 2020-12-24 | — | — | WO | claimed |
| CN-112110848-A | Novel diarylacylcarbazole compound and application thereof as sensitizer | 江苏英力科技发展有限公司 | 2020-12-22 | — | — | CN | claimed |
| US-10076517-B2 | Methods and pharmaceutical compositions for the treatment of fibrosis | INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE KA RECHERCHE MÉDICALE (FR) | 2018-09-18 | — | — | US | claimed |
| EP-2421825-B9 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-20 | — | — | EP | claimed |
| EP-2421825-B1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-01-01 | — | — | EP | claimed |
| EP-1597321-A1 | AZO METAL DYES AND OPTICAL DATA CARRIER CONTAINING ONE SUCH AZO METAL DYE AS A LIGHT ABSORBING COMPOUND IN THE INFORMATION LAYER | LANXESS Deutschland GmbH (DE) | 2005-11-23 | — | — | EP | claimed |
| EP-1042291-B1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE CO CHEM PHARM FAB (DE) | 2005-07-13 | — | — | EP | claimed |
| WO-2004072185-A1 | AZO METAL DYES AND OPTICAL DATA CARRIER CONTAINING ONE SUCH AZO METAL DYE AS A LIGHT ABSORBING COMPOUND IN THE INFORMATION LAYER | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | claimed |
| WO-2004072184-A1 | METAL COMPLEXES AS LIGHT-ABSORBING COMPOUNDS IN THE INFORMATION LAYER OF OPTICAL DATA CARRIERS | LANXESS DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | claimed |
| EP-1042291-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | Klinge Pharma GmbH (DE) | 2000-10-11 | — | — | EP | claimed |
| WO-1999031064-A1 | ARYL-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS | KLINGE PHARMA GMBH (DE) | 1999-06-24 | — | — | WO | claimed |
| EP-0849259-A1 | BENZIMIDAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1998-06-24 | — | — | EP | claimed |
| US-5212318-A | PREPARATION OF OMEGA-SUBSTITUTED ALKANAMIDE | EASTMAN KODAK COMPANY (US) | 1993-05-18 | — | — | US | claimed |
| US-5066652-A | ANTIULCER AGENTS | CHIESI FARMACEUTICI S.P.A. (IT) | 1991-11-19 | — | — | US | claimed |
| EP-0301422-A2 | Thiomethyl and sulfinylmethyl derivatives having gastric acid antisecretory activity, processes for the preparation thereof and pharmaceutical compositions containing them | CHIESI FARMACEUTICI S.p.A. (IT) | 1989-02-01 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10076517-B2 | Methods and pharmaceutical compositions for the treatment of fibrosis | LIPA, MGLL, PNLIP | KDM4E 1727/4885CYP3A4 1609/4885MAPT 4747/4885 |
| US-20220179309-A1 | PHOTOINITIATOR COMPOSITION CONTAINING ACYLCARBAZOLE DERIVATIVE AND CARBAZOLYL OXIME ESTER, AND USE THEREOF IN PHOTOCURABLE COMPOSITION | CYP2C19, ALAD, PPOX | KDM4E 455/4885CYP3A4 16/4885MAPT 1854/4885 |
| US-11947259-B2 | Photoinitiator composition containing acylcarbazole derivative and carbazolyl oxime ester, and use thereof in photocurable composition | CYP2C19, ALAD, PPOX | KDM4E 455/4885CYP3A4 16/4885MAPT 1854/4885 |
| US-20220185775-A1 | NOVEL DIAROYL CARBAZOLE COMPOUND AND USE THEREOF AS SENSITISING AGENT | PPOX, CBR3, CYP3A4 | KDM4E 561/4885CYP3A4 3/4885MAPT 1747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.