Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995135 | 0.85 | AVPR2 (0.48) | AVPR2AVPR1AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL8561524 | 0.80 | HPGD (0.46) | AVPR2AVPR1AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL8558397 | 0.80 | SMN1; SMN2 (0.47) | AVPR2AVPR1AHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7352575 | 0.78 | ALDH1A1 (0.56) | BCHEHPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL6993115 | 0.78 | AVPR2 (0.45) | AVPR2AVPR1ABCHEHPGDSMN1; SMN2 | |
| SCHEMBL21160915 | 0.78 | HPGD (0.49) | BCHEHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8562104 | 0.77 | HPGD (0.58) | HPGDSMN1; SMN2NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL6993733 | 0.76 | AVPR2 (0.73) | AVPR2AVPR1A | |
| SCHEMBL7349991 | 0.75 | L3MBTL1 (0.46) | BCHEHPGDSMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6990464 | 0.74 | ALDH1A1 (0.52) | BCHEHPGDSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709386-B1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMA CO LTD (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1097920-A1 | Intermediate for condensed benzazepine derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-0709386-A1 | FUSED BENZAZEPINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |