Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996955 | 0.80 | L3MBTL1 (0.47) | L3MBTL1POLBLMNAALDH1A1KDM4E | |
| SCHEMBL6992863 | 0.80 | L3MBTL1 (0.45) | L3MBTL1POLBLMNAALDH1A1KDM4E | |
| Methanesulfonamide SCHEMBL6999861 | 0.78 | CA2 (0.44) | L3MBTL1POLBLMNAALDH1A1CA12 | |
| SCHEMBL6995954 | 0.77 | L3MBTL1 (0.46) | L3MBTL1LMNAALDH1A1KDM4ETSHR | |
| SCHEMBL6989780 | 0.75 | SLC6A2 (0.46) | L3MBTL1LMNAALDH1A1KDM4EHTR2C | |
| Trifluoroacetamide SCHEMBL6993217 | 0.69 | SLC6A2 (0.40) | L3MBTL1LMNAALDH1A1KDM4E | |
| SCHEMBL7321616 | 0.67 | ALDH1A1 (0.48) | L3MBTL1LMNAALDH1A1KDM4ECA12 | |
| SCHEMBL28554357 | 0.67 | ALDH1A1 (0.49) | POLBALDH1A1KDM4ETSHRCA12 | |
| SCHEMBL7439813 | 0.66 | KDM4E (0.42) | L3MBTL1LMNAALDH1A1KDM4ETSHR | |
| SCHEMBL6205368 | 0.66 | ALDH1A1 (0.45) | L3MBTL1POLBALDH1A1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |