Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996955 | 0.83 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1KDM4EHTR2ADRD2 | |
| SCHEMBL8112492 | 0.79 | HTR2B (0.48) | HTR2ADRD2ADRA2BDRD1HTR2C | |
| SCHEMBL6996959 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KDM4EHTR2ADRD2 | |
| SCHEMBL8112494 | 0.77 | SIGMAR1 (0.49) | ALDH1A1KDM4EHTR2ADRD2ADRA2B | |
| SCHEMBL6992863 | 0.77 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1KDM4EHTR2ADRD2 | |
| Trifluoroacetamide SCHEMBL6993217 | 0.76 | SLC6A2 (0.40) | L3MBTL1ALDH1A1KDM4ELMNATACR1 | |
| SCHEMBL6989780 | 0.76 | SLC6A2 (0.46) | L3MBTL1ALDH1A1KDM4EHTR2CKCNH2 | |
| Methanesulfonamide SCHEMBL6999861 | 0.74 | CA2 (0.44) | L3MBTL1ALDH1A1HTR2CLMNASMN1; SMN2 | |
| SCHEMBL27597066 | 0.74 | CYP2C9 (0.50) | MEN1KMT2APTPN11TACR1 | |
| SCHEMBL6995950 | 0.73 | SLC6A12 (0.42) | ALDH1A1KDM4EHTR2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |