Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989780 | 0.74 | SLC6A2 (0.46) | KDM4EALDH1A1L3MBTL1LMNA | |
| SCHEMBL28554357 | 0.73 | ALDH1A1 (0.49) | KDM4EHPGDALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6205368 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL11099556 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL28553709 | 0.70 | AGTR1 (0.50) | KDM4EALDH1A1SMN1; SMN2LMNATSHR | |
| SCHEMBL5018903 | 0.69 | GABRA1 (0.48) | KDM4EHPGDALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9802590 | 0.68 | ABCB1 (0.47) | ALDH1A1L3MBTL1 | |
| SCHEMBL490857 | 0.67 | ALDH1A1 (0.53) | KDM4EHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL5925383 | 0.67 | KMT2A (0.44) | KDM4EALDH1A1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL6995954 | 0.67 | L3MBTL1 (0.46) | KDM4EALDH1A1SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621133-A | PREPARING A 1-(3,4-DIALKOXYPHENYL),3-HYDROXYALKANE(C6-C12) BY EPOXIDIZING A HALO DERIVATIVE WITH A BASE FOLLOWED BY DECYCLICIZING WITH AN ORGANOMETALLIC COMPOUND IN A SOLVENT; NAPHTHYLENES, ISOCHROMENES AND ISOTHIOCHROMENES | DENINNO MICHAEL P (US) | 1997-04-15 | — | — | US | disclosed |
| US-5591884-A | PROTECTED HYDROXYALKYLCATECHOL INTERMEDIATES | ABBOTT LABORATORIES (US) | 1997-01-07 | — | — | US | disclosed |
| WO-1996038435-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1996-12-05 | — | — | WO | disclosed |
| EP-0474767-B1 | DOPAMINE AGONISTS | ABBOTT LAB (US) | 1996-02-21 | — | — | EP | disclosed |
| EP-0474767-A4 | DOPAMINE AGONISTS | — | 1992-07-08 | — | — | EP | disclosed |
| EP-0474767-A1 | DOPAMINE AGONISTS. | ABBOTT LAB (US) | 1992-03-18 | — | — | EP | disclosed |
| WO-1990015056-A1 | DOPAMINE AGONISTS | ABBOTT LABORATORIES (US) | 1990-12-13 | — | — | WO | disclosed |