Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.31 |
| ▸ | MGAM | O43451 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SI | P14410 | 2/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801959 | 0.79 | IDO1 (0.36) | RIPK1IDO1F7 | |
| SCHEMBL5733606 | 0.65 | IDO1 (0.42) | IDO1 | |
| SCHEMBL3259988 | 0.64 | KDM4E (0.35) | — | |
| SCHEMBL6998276 | 0.61 | NPC1 (0.36) | IDO1MGAMGAASIMGAM2 | |
| SCHEMBL17502486 | 0.58 | TYMS (0.32) | — | |
| SCHEMBL8962806 | 0.57 | IDO1 (0.56) | RIPK1IDO1 | |
| SCHEMBL4314003 | 0.56 | ACHE (0.46) | MGAMGAASIMGAM2 | |
| SCHEMBL4314005 | 0.56 | ACHE (0.46) | GAAF7 | |
| SCHEMBL75450 | 0.55 | ALDH1A1 (0.60) | IDO1GAAF7 | |
| SCHEMBL29437860 | 0.55 | ALDH1A1 (0.60) | IDO1GAAF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2315755-B1 | SYNTHESIS OF DIHYDROTHIENO[3,2-d]PYRIMIDINE DIOLS AND SIMILAR PYRIMIDINE DIOLS | BOEHRINGER INGELHEIM INT (DE) | 2012-08-08 | — | — | EP | disclosed |
| EP-0775120-B1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2003-06-04 | — | — | EP | disclosed |
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |