Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | HPN | P05981 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | ADK | P55263 | 1/20 | 0.30 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998276 | 0.79 | NPC1 (0.36) | IDO1NPC1RAB9AGSK3BNUDT1 | |
| SCHEMBL7000751 | 0.79 | RIPK1 (0.32) | IDO1F7RIPK1 | |
| SCHEMBL4838743 | 0.67 | MAPT (0.37) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL5733606 | 0.63 | IDO1 (0.42) | IDO1ALDH1A1 | |
| SCHEMBL3095793 | 0.60 | RAB9A (0.46) | NPC1RAB9AGSK3BADKMAPT | |
| SCHEMBL9305483 | 0.60 | RAB9A (0.50) | NPC1RAB9AMAPTKMT2AKDM4E | |
| SCHEMBL9305473 | 0.60 | ACHE (0.43) | RAB9AGUSBF7MAPTHPGD | |
| SCHEMBL8962806 | 0.55 | IDO1 (0.56) | IDO1NPC1RAB9AF2F10 | |
| SCHEMBL66295 | 0.54 | PSMB8 (0.59) | NPC1RAB9ANUDT1MAPTHPGD | |
| SCHEMBL66296 | 0.54 | NOS1 (0.44) | NPC1RAB9AGUSBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775120-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996005177-A1 | NOVEL PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 1996-02-22 | — | — | WO | disclosed |