Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27562876 | 0.83 | PARP1 (0.34) | ALDH1A1L3MBTL1HTTLMNAKDM4E | |
| SCHEMBL7000445 | 0.83 | ADRA2A (0.41) | ALDH1A1L3MBTL1USP2HTTLMNA | |
| SCHEMBL7001646 | 0.82 | SIGMAR1 (0.41) | ALDH1A1GAAHSD17B10ADRA1DADRA1A | |
| SCHEMBL27412635 | 0.70 | DRD1 (0.38) | LMNAKDM4ESMN1; SMN2PARP1HPGD | |
| SCHEMBL6993213 | 0.70 | ACHE (0.46) | POLBMEN1KMT2A | |
| SCHEMBL6994737 | 0.70 | ADRA2A (0.41) | KDM4EMAPTHSD17B10MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27410357 | 0.70 | DRD1 (0.38) | LMNAKDM4ESMN1; SMN2PARP1HPGD | |
| SCHEMBL6988766 | 0.69 | DRD1 (0.38) | ALDH1A1HTTSMN1; SMN2GAATSHR | |
| SCHEMBL6996299 | 0.69 | DRD1 (0.40) | L3MBTL1LMNAKDM4ESMN1; SMN2PARP1 | |
| SCHEMBL6988760 | 0.69 | DRD1 (0.38) | ALDH1A1HTTSMN1; SMN2GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | claimed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | claimed |
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |