SCHEMBL71452

SCHEMBL71452

CCCC(C)c1ccc(O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TYR P14679 5/20 0.49
SRC P12931 1/20 0.45
TSHR P16473 2/20 0.42
HTT P42858 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX5 P09917 1/20 0.41
MAPT P10636 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL469144 0.89 TYR (0.49) TYRSRCTSHRHTTMEN1
SCHEMBL70058 0.86 TYR (0.51) TYRSRCTSHRHTTMEN1
SCHEMBL18986199 0.85 TYR (0.49) TYRSRC
SCHEMBL7950538 0.85 RORC (0.47) TYRTSHRHTTMEN1TP53
SCHEMBL29492442 0.84 TSHR (0.61) TYRTSHRALOX15
SCHEMBL1104213 0.84 TSHR (0.61) TYRTSHRALOX15
SCHEMBL8386062 0.84 TYR (0.45) TYRTSHRHTTMEN1TP53
SCHEMBL30893093 0.83 SRC (0.64) SRCTSHRHTTMEN1TP53
SCHEMBL22267492 0.83 ESR2 (0.44) TYRSRCTSHRTP53CYP3A4
SCHEMBL5497338 0.83 SRC (0.44) TYRSRCTSHRMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11129781-B2 Agent for hair deforming treatment KAO CORPORATION (JP) 2021-09-28 US disclosed
US-11045402-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-06-29 US disclosed
US-10959925-B2 Hair cosmetic composition KAO CORPORATION (JP) 2021-03-30 US disclosed
EP-3228302-B1 HAIR DEFORMATION TREATMENT AGENT KAO CORP (JP) 2020-09-02 EP disclosed
CN-106999382-B Hair deforming agent 花王株式会社 2020-07-10 CN disclosed
CN-106999380-B Hair deforming agent 花王株式会社 2020-05-05 CN disclosed
US-20190290564-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-09-26 US disclosed
US-20190254943-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-08-22 US disclosed
US-20190224093-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2019-07-25 US disclosed
US-20190125052-A1 METHOD FOR TREATING HAIR KAO CORPORATION (JP) 2019-05-02 US disclosed
EP-3228302-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
EP-3228300-A1 HAIR DEFORMATION TREATMENT AGENT Kao Corporation (JP) 2017-10-11 EP disclosed
CN-106999382-A Hair deformation process agent 花王株式会社 2017-08-01 CN disclosed
CN-106999380-A Hair deforming agent 花王株式会社 2017-08-01 CN disclosed
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
JP-2006124358-A 4-ALKYLRESORCINOL DERIVATIVE AND BLEACHING AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT SHISEIDO CO LTD 2006-05-18 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 TYR 134/4885SRC 1380/4885TSHR 3263/4885
US-11045402-B2 Hair cosmetic composition CUTA, GRHPR, POLR1C TYR 6/4885SRC 2180/4885TSHR 4584/4885
US-10959925-B2 Hair cosmetic composition CUTA, POLR1C, GRHPR TYR 4/4885SRC 1580/4885TSHR 4675/4885
US-20190254943-A1 HAIR COSMETIC COMPOSITION CUTA, POLR1C, GRHPR TYR 4/4885SRC 1580/4885TSHR 4675/4885
US-20190125052-A1 METHOD FOR TREATING HAIR GRHPR, TYR, POLR1C TYR 2/4885SRC 869/4885TSHR 3985/4885
US-20190224093-A1 HAIR COSMETIC COMPOSITION CUTA, GRHPR, POLR1C TYR 6/4885SRC 2180/4885TSHR 4584/4885
US-11129781-B2 Agent for hair deforming treatment GRHPR, SLC26A4, COL1A1 TYR 98/4885SRC 2064/4885TSHR 4155/4885
US-20190290564-A1 HAIR COSMETIC COMPOSITION GRHPR, POLR1C, TYR TYR 3/4885SRC 1942/4885TSHR 4636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.