Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846884 | 0.82 | RAB9A (0.33) | AOC3RAB9AALDH1A1POLBLMNA | |
| SCHEMBL6847091 | 0.81 | AOC3 (0.42) | AOC3ALDH1A1POLB | |
| SCHEMBL6850977 | 0.78 | PDE3B (0.37) | AOC3RAB9AALDH1A1POLB | |
| SCHEMBL6849755 | 0.77 | ALDH1A1 (0.40) | AOC3RAB9AALDH1A1 | |
| SCHEMBL6955858 | 0.75 | HRH3 (0.47) | PARP15PARP10PARP2RAB9A | |
| SCHEMBL6846885 | 0.75 | RAB9A (0.36) | RAB9AALDH1A1POLBLMNA | |
| SCHEMBL6851075 | 0.74 | SIRT1 (0.40) | RAB9ALMNA | |
| SCHEMBL6963222 | 0.73 | METAP2 (0.44) | RAB9AALDH1A1POLB | |
| SCHEMBL6967672 | 0.71 | L3MBTL1 (0.43) | AOC3RAB9ALMNA | |
| SCHEMBL28007449 | 0.71 | NPC1 (0.40) | RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |