Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007438 | 0.86 | SLC16A1 (0.44) | ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7008632 | 0.80 | BRD4 (0.41) | ALDH1A1LMNAKDRPTK2PIK3CD | |
| SCHEMBL5864573 | 0.80 | PDE3B (0.44) | ALDH1A1LMNASMN1; SMN2NPC1KDM4E | |
| SCHEMBL7006914 | 0.78 | PDE2A (0.45) | ALDH1A1LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7013217 | 0.78 | KMT2A (0.44) | ALDH1A1LMNASMN1; SMN2KDRPTK2 | |
| SCHEMBL7007770 | 0.73 | ADORA2B (0.35) | ALDH1A1LMNA | |
| SCHEMBL1059693 | 0.68 | RAB9A (0.64) | LMNASMN1; SMN2NPC1RAB9AHDAC6 | |
| SCHEMBL5864675 | 0.67 | LMNA (0.44) | ALDH1A1LMNASMN1; SMN2RECQLMAPT | |
| SCHEMBL6808474 | 0.67 | MAPK1 (0.49) | ALDH1A1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7010147 | 0.66 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1107973-B1 | NOVEL THIENO[2,3-d]PYRIMIDINEDIONES, PROCESS FOR THEIR PREPARATION AND USE THEREOF IN THERAPY | ASTRAZENECA AB (SE) | 2003-11-05 | — | — | EP | claimed |