Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014984 | 1.00 | TSHR (0.32) | TSHRMPOALDH1A1HPGDCYP1A2 | |
| SCHEMBL7014473 | 0.87 | TSHR (0.33) | TSHRALDH1A1CYP1A2 | |
| SCHEMBL7014468 | 0.87 | TSHR (0.33) | TSHRALDH1A1CYP1A2 | |
| SCHEMBL7014430 | 0.74 | MAPT (0.48) | ALDH1A1CYP1A2KDM4E | |
| SCHEMBL7014427 | 0.74 | MAPT (0.48) | ALDH1A1CYP1A2KDM4E | |
| SCHEMBL7016851 | 0.73 | ADORA2A (0.33) | ALDH1A1HPGDKDM4E | |
| SCHEMBL7019903 | 0.73 | XDH (0.42) | ALDH1A1HPGDKDM4E | |
| SCHEMBL7022754 | 0.73 | ADORA3 (0.36) | ALDH1A1HPGDKDM4E | |
| SCHEMBL7022645 | 0.73 | QPCT (0.32) | ALDH1A1 | |
| SCHEMBL7016847 | 0.73 | ADORA2A (0.33) | ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1357114-A1 | Substituted pyrimidin-2,4(1H,3H)-diones as inhibitors of Matrix Metalloproteinases (MMP) | IBFB GmbH Privates Institut für biomedizinische Forschung und Beratung (DE) | 2003-10-29 | — | — | EP | disclosed |