Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ANPEP | P15144 | 3/20 | 0.34 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700495 | 0.84 | LMNA (0.37) | ALDH1A1TDP1FDPS | |
| SCHEMBL700293 | 0.74 | — | — | |
| SCHEMBL29260835 | 0.73 | METAP1 (0.39) | METAP1LAP3FDPS | |
| SCHEMBL103934 | 0.70 | — | — | |
| Phosphoric Acid SCHEMBL14953332 | 0.69 | TSHR (0.32) | ALDH1A1ANPEPLAP3ERAP1 | |
| Phosphoric Acid SCHEMBL16541047 | 0.65 | TSHR (0.39) | ALDH1A1TDP1FDPS | |
| SCHEMBL701768 | 0.65 | — | — | |
| SCHEMBL336108 | 0.65 | TYMS (0.45) | ALDH1A1ANPEPTDP1 | |
| 3-Methylbutanol SCHEMBL4718917 | 0.65 | ALDH1A1 (0.41) | METAP1ALDH1A1ANPEPLAP3ERAP1 | |
| SCHEMBL11203643 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252584-B1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME INC (US) | 2016-12-07 | — | — | EP | disclosed |
| US-8445292-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120107942-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2012-05-03 | — | — | US | disclosed |
| US-8163910-B2 | Amide-substituted xanthene dyes | ELITECH HOLDING B.V. (NL) | 2012-04-24 | — | — | US | disclosed |
| US-8124792-B2 | Compounds and methods for rapid labeling of N-glycans | PROZYME, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| EP-2252584-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | Prozyme, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |
| US-20090258437-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2009-10-15 | — | — | US | disclosed |
| WO-2009100155-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | PROZYME, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009046165-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258437-A1 | COMPOUNDS AND METHODS FOR RAPID LABELING OF N-GLYCANS | B3GNT2, FUT5, FUT6 | METAP1 3797/4885ALDH1A1 2931/4885ANPEP 125/4885 |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | ANXA5, PHOSPHO1, TPST2 | METAP1 4180/4885ALDH1A1 4277/4885ANPEP 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.