Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718509 | 0.73 | — | — | |
| SCHEMBL10376827 | 0.72 | BTN3A1 (0.41) | TYMSBTN3A1ALDH1A1LMNACYP3A4 | |
| SCHEMBL21385310 | 0.71 | — | — | |
| SCHEMBL11332095 | 0.71 | — | — | |
| SCHEMBL585465 | 0.71 | — | — | |
| SCHEMBL103934 | 0.71 | — | — | |
| Methane SCHEMBL28455124 | 0.71 | — | — | |
| SCHEMBL8352725 | 0.69 | TYMS (0.69) | TYMSALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL81370 | 0.69 | TYMS (0.69) | TYMSALDH1A1LMNACYP3A4NFKB1 | |
| SCHEMBL5163771 | 0.69 | ALDH1A1 (0.46) | TYMSBTN3A1ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319823-A1 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | North Carolina State University (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022216927-A9 | PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-09-14 | — | — | WO | disclosed |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2021-02-16 | — | — | US | disclosed |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | NORTH CAROLINA STATE UNIVERSITY (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | UNITED STATES DEPARTMENT OF ENERGY | 2019-10-10 | — | — | US | disclosed |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | UNITED STATES DEPARTMENT OF ENERGY | 2019-08-22 | — | — | US | disclosed |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | NORTH CAROLINA STATE UNIVERSITY (US) | 2019-04-09 | — | — | US | disclosed |
| WO-2018102252-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-06-07 | — | — | WO | disclosed |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | UNIV NORTH CAROLINA STATE (US) | 2018-03-15 | — | — | US | disclosed |
| WO-2018035281-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-02-22 | — | — | WO | disclosed |
| US-20090054432-A1 | 2-(2-Hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-Carboxamidine Derivatives as Factor VIIA Inhibitors | PHARMACYLICS, INC. A DELAWARE CORPORATION (US) | 2009-02-26 | — | — | US | disclosed |
| US-7479502-B2 | 2-(2-hydroxybiphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors | PHARMACYCLICS, INC. (US) | 2009-01-20 | — | — | US | disclosed |
| EP-1848778-A2 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | North Carolina State University (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2007078498-A1 | GEOMETRIC SYNTHESIS OF PORPHYRIN RODS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-07-05 | — | — | US | disclosed |
| WO-2007047925-A2 | SWALLOWTAIL MOTIFS FOR IMPARTING WATER SOLUBILITY TO PORPHYRINIC COMPOUNDS | NORTH CAROLINA STATE UNIVERSITY (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20060205942-A1 | e.g. 2-{2-[545-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-dihydroxy-5'-sulthmoyl-biphenyl-3-yl]-acetylsmino}-succinamic; anticoagulant, anticarcinogenic, antiinflammatory agent; deep vein thrombosis, rheumatoid arthritis, stroke | PHARMACYCLICS LLC | 2006-09-14 | — | — | US | disclosed |
| WO-2006089122-A2 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | NORTH CAROLINA STATE UNIVERSITY (US) | 2006-08-24 | — | — | WO | disclosed |
| EP-1569912-A2 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004050637-A2 | 2-(2-HYDROXYBIPHENYL-3-YL)-1H-BENZOIMIDAZOLE-5-CARBOXAMIDINE DERIVATIVES AS FACTOR VIIA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155963-A1 | Geometric synthesis of porphyrin rods | PPOX, DLD, PYCR1 | TYMS 1124/4885BTN3A1 2556/4885ALDH1A1 883/4885 |
| US-10253033-B2 | De novo synthesis of bacteriochlorins | BCL6, ALDH1A2, ALAD | TYMS 1094/4885BTN3A1 1184/4885ALDH1A1 263/4885 |
| US-20190256521-A1 | NORTHERN-SOUTHERN ROUTE TO SYNTHESIS OF BACTERIOCHLORINS | DLD, HCCS, PPIF | TYMS 496/4885BTN3A1 741/4885ALDH1A1 2805/4885 |
| US-10836774-B2 | Methods for making bacteriochlorin macrocycles comprising an annulated isocyclic ring and related compounds | PPOX, MRPL19, PYCR1 | TYMS 1748/4885BTN3A1 470/4885ALDH1A1 1630/4885 |
| US-10919904-B2 | Northern-southern route to synthesis of bacteriochlorins | DLD, HCCS, PPIF | TYMS 496/4885BTN3A1 741/4885ALDH1A1 2805/4885 |
| US-20060205942-A1 | e.g. 2-{2-[545-carbamimidoyl-1H-benzoimidazol-2-yl)-6,2'-dihydroxy-5'-sulthmoyl-biphenyl-3-yl]-acetylsmino}-succinamic; anticoagulant, anticarcinogenic, antiinflammatory agent; deep vein thrombosis, rheumatoid arthritis, stroke | F7, F9, F5 | TYMS 1503/4885BTN3A1 1015/4885ALDH1A1 1275/4885 |
| US-20190308985-A1 | METHODS FOR MAKING BACTERIOCHLORIN MACROCYCLES COMPRISING AN ANNULATED ISOCYCLIC RING AND RELATED COMPOUNDS | PPOX, PPIC, ALAD | TYMS 783/4885BTN3A1 502/4885ALDH1A1 1003/4885 |
| US-20180072746-A1 | DE NOVO SYNTHESIS OF BACTERIOCHLORINS | BCL6, ALDH1A2, ALAD | TYMS 1094/4885BTN3A1 1184/4885ALDH1A1 263/4885 |
| US-20090054432-A1 | 2-(2-Hydroxybiphenyl-3-yl)-1H-Benzoimidazole-5-Carboxamidine Derivatives as Factor VIIA Inhibitors | F13B, HABP2, F7 | TYMS 2494/4885BTN3A1 1155/4885ALDH1A1 2997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.