Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | UBE2N | P61088 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7013633 | 0.87 | LMNA (0.51) | TRPA1LMNAMAPK1HTTMAOA | |
| SCHEMBL7012643 | 0.83 | TRPA1 (0.58) | TRPA1RXFP1L3MBTL1MAPT | |
| SCHEMBL7016345 | 0.83 | LMNA (0.66) | LMNAMAPK1SMN1; SMN2HTTUBE2N | |
| SCHEMBL7009394 | 0.81 | TRPA1 (0.61) | TRPA1KDM4ESMN1; SMN2ABCC8KCNJ11 | |
| SCHEMBL7102075 | 0.80 | KMT2A (0.46) | LMNAMAPK1KDM4ESMN1; SMN2ADORA2B | |
| SCHEMBL8644499 | 0.79 | LMNA (0.51) | LMNAMAPK1KDM4ESMN1; SMN2HTT | |
| SCHEMBL7011108 | 0.71 | LMNA (0.84) | LMNAMAPK1SMN1; SMN2HTTUBE2N | |
| Hydrochloric Acid SCHEMBL7019827 | 0.70 | LMNA (0.82) | LMNAMAPK1SMN1; SMN2HTTUBE2N | |
| SCHEMBL8644491 | 0.70 | RXFP1 (0.59) | LMNAKDM4ESMN1; SMN2HTTADORA2B | |
| Hydrochloric Acid SCHEMBL7013530 | 0.69 | L3MBTL1 (0.39) | LMNAKMT2AL3MBTL1PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |