Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016155 | 0.80 | TRPA1 (0.43) | KMT2AL3MBTL1ADORA2BSMN1; SMN2RXFP1 | |
| SCHEMBL7013633 | 0.76 | LMNA (0.51) | RAB9ATSHRMAPTMAPK1LMNA | |
| SCHEMBL7012643 | 0.75 | TRPA1 (0.58) | L3MBTL1ALDH1A1RXFP1MAPT | |
| SCHEMBL7015781 | 0.75 | KMT2A (0.45) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7017592 | 0.74 | KMT2A (0.44) | KMT2ANPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL7009394 | 0.72 | TRPA1 (0.61) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7017996 | 0.70 | LMNA (0.48) | KMT2ARAB9AL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL7015205 | 0.69 | L3MBTL1 (0.57) | RAB9AL3MBTL1ALDH1A1HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL7018696 | 0.68 | KMT2A (0.43) | KMT2ANPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL7013690 | 0.68 | KMT2A (0.47) | KMT2ANPC1RAB9AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |