Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012643 | 0.89 | TRPA1 (0.58) | MAPTTRPA1HDAC1HDAC8HDAC6 | |
| SCHEMBL7016155 | 0.87 | TRPA1 (0.43) | LMNAMAPK1POLBMAPTHTT | |
| SCHEMBL7009394 | 0.86 | TRPA1 (0.61) | TRPA1MAOB | |
| SCHEMBL7021039 | 0.79 | MAOA (0.50) | LMNAMAPK1POLBMAPTHTT | |
| SCHEMBL7011108 | 0.79 | LMNA (0.84) | LMNAMAPK1POLBMAPTHTT | |
| Hydrochloric Acid SCHEMBL7019827 | 0.78 | LMNA (0.82) | LMNAMAPK1POLBMAPTHTT | |
| SCHEMBL7102075 | 0.76 | KMT2A (0.46) | LMNAMAPK1MAPTRAB9ATSHR | |
| SCHEMBL7017096 | 0.75 | MAPK1 (0.53) | LMNAMAPK1MAPTHTTMAOA | |
| SCHEMBL17493249 | 0.74 | TRPC5 (0.49) | LMNAMAPK1POLBMAPTTRPA1 | |
| SCHEMBL8642267 | 0.74 | LMNA (0.55) | LMNAMAPK1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |