SCHEMBL309967

SCHEMBL309967

Cc1nccn1C(=O)n1ccnc1C

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.39
ALDH1A1 P00352 3/20 0.38
KMT2A Q03164 3/20 0.38
ALPL P05186 2/20 0.38
ALPG P10696 2/20 0.38
POLB P06746 1/20 0.38
ALPI P09923 1/20 0.38
PLAA Q9Y263 1/20 0.38
GFER P55789 1/20 0.37
NOS1 P29475 1/20 0.36
CYP2E1 P05181 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2A6 P11509 1/20 0.35
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1165059 0.85 FDPS (0.39) FDPSALDH1A1KMT2AALPLALPG
SCHEMBL7017228 0.83 ALDH1A1 (0.41) ALDH1A1ALPLALPGALPIPLAA
SCHEMBL298299 0.83
SCHEMBL9502453 0.83
SCHEMBL446875 0.81
Hydrochloric Acid SCHEMBL16433303 0.79 PARP1 (0.42) FDPSALDH1A1KMT2AALPLALPG
SCHEMBL14825913 0.78 LPO (0.44) FDPSKMT2AALPLALPGALPI
SCHEMBL8761396 0.78 FDPS (0.39) FDPSALDH1A1KMT2AALPLALPG
SCHEMBL13114302 0.78 FDPS (0.39) FDPSALDH1A1KMT2AALPLALPG
SCHEMBL13134140 0.78 ALDH1A1 (0.41) FDPSALDH1A1KMT2AALPLALPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624129-B2 Crosslinked butyrate or butyrate-formate derivatives of hyaluronic acid and the crosslinking thereof BMG PHARMA S.P.A. (IT) 2026-05-12 US claimed
US-20220411541-A1 CROSSLINKED BUTYRATE OR BUTYRATE-FORMATE DERIVATIVES OF HYALURONIC ACID AND THE CROSSLINKING THEREOF BMG PHARMA S.P.A. (IT) 2022-12-29 US claimed
EP-3507320-B1 USE OF AN ORGANOCARBONATE MODIFIED PRE-POLYMER AS AN EDUCT FOR THE PRODUCTION OF ISOCYANATE-FREE AND ISOTHIOCYANATE-FREE ALKOXYSILANE POLYMERS MERZ BENTELI AG (CH) 2020-10-21 EP claimed
US-20190352461-A1 USE OF AN ORAGANOCARBONATE-MODIFIED PREPOLYMER AS REACTANT FOR PREPARATION OF ISOCYANATE-FREE AND ISOTHIOCYANATE-FREE ALKOXYSILANE POLYMERS MERZ+BENTELI AG (CH) 2019-11-21 US claimed
EP-2558441-B1 PROCESS FOR PRODUCING ISOCYANATES 3M INNOVATIVE PROPERTIES CO (US) 2018-05-30 EP claimed
EP-2909177-B1 PROCESS FOR PREPARING ROFLUMILAST INTERQUIM SA (ES) 2017-03-29 EP claimed
US-9321726-B2 Process for preparing roflumilast INTERQUIM, S.A. (ES) 2016-04-26 US claimed
US-20150246884-A1 PROCESS FOR PREPARING ROFLUMILAST INTERQUIM, S.A. (ES) 2015-09-03 US claimed
US-9006480-B2 Process for producing isocyanates 3M INNOVATIVE PROPERTIES COMPANY (US) 2015-04-14 US claimed
US-20130023694-A1 PROCESS FOR PRODUCING ISOCYANATES 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-24 US claimed
EP-2377847-A1 Process for producing isocyanates 3M Innovative Properties Company (US) 2011-10-19 EP claimed
WO-2008023383-A1 NOVEL PROCESS FOR THE PREPARATION OF TELITHROMYCIN ALEMBIC LIMITED (IN) 2008-02-28 WO claimed
US-20080051352-A1 Novel process for the preparation of telithromycin ALEMBIC LIMITED (IN) 2008-02-28 US claimed
EP-0004570-B1 THIOL ESTERS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND A PROCESS FOR PREPARING CEPHALOSPORIN COMPOUNDS USING THE SAME Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-04-14 EP claimed
EP-0004570-A1 Thiol esters, process for their preparation, pharmaceutical compositions containing them and a process for preparing cephalosporin compounds using the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1979-10-17 EP claimed
US-12624129-B2 Crosslinked butyrate or butyrate-formate derivatives of hyaluronic acid and the crosslinking thereof BMG PHARMA S.P.A. (IT) 2026-05-12 US disclosed
EP-4161580-B1 CANNABINOID-HYALURONIC ACID BIOCONJUGATES LONDON PHARMACEUTICALS AND RES CORPORATION (CA) 2026-03-18 EP disclosed
US-3992409-A ANTICOLINERGIC AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-16 US disclosed
US-3984397-A CYCLIZATION FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-10-05 US disclosed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080051352-A1 Novel process for the preparation of telithromycin TREH, CYP3A7, CYP3A4 FDPS 219/4885ALDH1A1 4146/4885KMT2A 3599/4885
US-12624129-B2 Crosslinked butyrate or butyrate-formate derivatives of hyaluronic acid and the crosslinking thereof CD44, MUC1, FGB FDPS 248/4885ALDH1A1 340/4885KMT2A 3443/4885
US-20130023694-A1 PROCESS FOR PRODUCING ISOCYANATES IDH2, IDH1, IDH3A FDPS 39/4885ALDH1A1 313/4885KMT2A 878/4885
US-20150246884-A1 PROCESS FOR PREPARING ROFLUMILAST ESD, DNTT, HPD FDPS 388/4885ALDH1A1 212/4885KMT2A 1021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.