SCHEMBL7017886

SCHEMBL7017886

CCCC1=C(C(=O)O)C(c2cccc(Br)c2Br)c2c[nH]nc2N1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CACNA1D Q01668 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6293602 0.89 NR3C2 (0.41) CACNA1D
SCHEMBL7435633 0.86 CACNA1C (0.36) CACNA1D
SCHEMBL7438969 0.86 CACNA1C (0.36) CACNA1D
SCHEMBL7435806 0.83 MEN1 (0.39) CACNA1D
SCHEMBL7429502 0.83 CYP2C9 (0.42) CACNA1D
SCHEMBL7441431 0.83 PYGL (0.39) CACNA1D
SCHEMBL7433747 0.82 ALDH1A1 (0.37)
SCHEMBL7018953 0.81 GAA (0.41)
SCHEMBL7434003 0.81 CACNA1D (0.33) CACNA1D
SCHEMBL7023229 0.81 KDM4E (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1355909-A2 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF Mitsubishi Pharma Corporation (JP) 2003-10-29 EP disclosed
WO-2002062795-A9 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF MITSUBISHI PHARMA CORP (JP) 2002-10-10 WO disclosed
WO-2002062795-A2 DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF MITSUBISHI PHARMA CORPORATION (JP) 2002-08-15 WO disclosed