Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7433747 | 0.91 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10SMN1; SMN2PPARA | |
| SCHEMBL6297388 | 0.89 | PKM (0.47) | GAAALDH1A1KDM4EGLAHSD17B10 | |
| SCHEMBL7148024 | 0.82 | KDM4E (0.39) | GAAALDH1A1KDM4EHSD17B10TSHR | |
| SCHEMBL7017886 | 0.81 | CACNA1D (0.31) | — | |
| SCHEMBL7429502 | 0.81 | CYP2C9 (0.42) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL7435806 | 0.81 | MEN1 (0.39) | ALDH1A1KDM4EHPGDPKMTSHR | |
| SCHEMBL7441431 | 0.81 | PYGL (0.39) | GAAALDH1A1KDM4EGLAHSD17B10 | |
| SCHEMBL6296486 | 0.80 | NR3C2 (0.40) | GAAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6292394 | 0.80 | DHFR (0.47) | ALDH1A1KDM4EHPGDPKMTSHR | |
| SCHEMBL7434003 | 0.79 | CACNA1D (0.33) | ALDH1A1HPGDSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355909-A2 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062795-A2 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORPORATION (JP) | 2002-08-15 | — | — | WO | disclosed |