Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 7/20 | 0.38 |
| ▸ | CDK1 | P06493 | 7/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 7/20 | 0.38 |
| ▸ | GSK3A | P49840 | 6/20 | 0.38 |
| ▸ | GSK3B | P49841 | 6/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019826 | 0.82 | RIPK1 (0.42) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL7103387 | 0.77 | KDM4E (0.39) | CCNB2CDK1CCNB1CCNB3CDK5 | |
| SCHEMBL7016752 | 0.75 | EGFR (0.35) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL6286415 | 0.74 | TUBB4A (0.38) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL6494995 | 0.70 | KDM4E (0.38) | CCNB2CDK1CCNB1CCNB3FYN | |
| SCHEMBL6286410 | 0.69 | PARP1 (0.42) | KDM4EMAPT | |
| SCHEMBL7016833 | 0.68 | CCNB2 (0.42) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL7019380 | 0.68 | RIPK1 (0.41) | CCNB2CDK1CCNB1CCNB3GSK3A | |
| SCHEMBL7104266 | 0.65 | PDGFRB (0.38) | KDM4EMAPT | |
| SCHEMBL14438040 | 0.63 | NR3C1 (0.37) | CCNB2CDK1CCNB1CCNB3GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294718-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY LLC (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096336-A2 | 6,5-FUSED BICYCLIC HETEROCYCLES | WARNER-LAMBERT COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |