Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13453375 | 0.72 | HTR2C (0.36) | — | |
| SCHEMBL7019655 | 0.65 | CA12 (0.37) | TSHRCYP3A4 | |
| SCHEMBL29946198 | 0.62 | MAOA (0.33) | — | |
| SCHEMBL11189916 | 0.58 | TSHR (0.72) | TSHRCYP3A4 | |
| SCHEMBL6818155 | 0.58 | — | — | |
| SCHEMBL15199334 | 0.56 | FBP1 (0.58) | — | |
| SCHEMBL23537533 | 0.56 | CYP1A2 (0.41) | CYP3A4 | |
| SCHEMBL4464974 | 0.56 | TSHR (0.55) | TSHRCYP3A4 | |
| SCHEMBL28662585 | 0.55 | MAOA (0.42) | — | |
| SCHEMBL531072 | 0.53 | ALDH1A1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705832-B1 | Serotonergic modulators | LILLY CO ELI (GB) | 2003-08-13 | — | — | EP | disclosed |
| US-5563147-A | CENTRAL NERVOUS SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0705832-A1 | Serotonergic modulators | LILLY INDUSTRIES LIMITED (GB) | 1996-04-10 | — | — | EP | disclosed |