Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TNF | P01375 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18909733 | 0.86 | TDP1 (0.49) | TDP1ALDH1A1TNFHPGDKDM4E | |
| SCHEMBL701659 | 0.81 | TDP1 (0.45) | TDP1ALDH1A1RAB9AHPGDNPSR1 | |
| SCHEMBL701660 | 0.81 | TDP1 (0.45) | TDP1ALDH1A1RAB9AHPGDNPSR1 | |
| SCHEMBL701159 | 0.80 | ALDH1A1 (0.44) | TDP1ALDH1A1TNFHPGDKDM4E | |
| SCHEMBL21788258 | 0.79 | NR1H2 (0.44) | TDP1ALDH1A1RAB9ACDC25ANPC1 | |
| SCHEMBL13810700 | 0.78 | MAP2K7 (0.40) | TDP1ALDH1A1RAB9ATNFHPGD | |
| SCHEMBL4626053 | 0.76 | TDP1 (0.59) | TDP1ALDH1A1RAB9ATNFPOLB | |
| SCHEMBL11914467 | 0.76 | TDP1 (0.59) | TDP1ALDH1A1RAB9ATNFPOLB | |
| SCHEMBL9933904 | 0.76 | TDP1 (0.59) | TDP1ALDH1A1RAB9ATNFPOLB | |
| SCHEMBL21082757 | 0.76 | MGLL (0.34) | ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220326230-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED (US) | 2022-10-13 | — | — | US | disclosed |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2022-03-08 | — | — | US | disclosed |
| US-20200225217-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED (US) | 2020-07-16 | — | — | US | disclosed |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2020-02-11 | — | — | US | disclosed |
| EP-1659881-B1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-3431464-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| US-20180364220-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED | 2018-12-20 | — | — | US | disclosed |
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| US-20150093339-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED | 2015-04-02 | — | — | US | disclosed |
| US-8895050-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-20120201763-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-8124121-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX, INC. | 2009-04-30 | — | — | US | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| EP-1659881-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
| WO-2005041684-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | FIRMENICH INCORPORATED | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | TDP1 3961/4885ALDH1A1 959/4885RAB9A 4241/4885 |
| US-20150093339-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TDP1 3974/4885ALDH1A1 1089/4885RAB9A 4173/4885 |
| US-20200225217-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R40 | TDP1 4029/4885ALDH1A1 1080/4885RAB9A 4209/4885 |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | TDP1 3961/4885ALDH1A1 959/4885RAB9A 4241/4885 |
| US-20120201763-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TDP1 3974/4885ALDH1A1 1089/4885RAB9A 4173/4885 |
| US-20180364220-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TDP1 3974/4885ALDH1A1 1089/4885RAB9A 4173/4885 |
| US-20220326230-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TDP1 3974/4885ALDH1A1 1089/4885RAB9A 4173/4885 |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TDP1 3974/4885ALDH1A1 1089/4885RAB9A 4173/4885 |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS2R40, TAS1R2, TAS1R1 | TDP1 3965/4885ALDH1A1 1037/4885RAB9A 4185/4885 |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | TAS2R40, TAS2R4, TAS2R30 | TDP1 4494/4885ALDH1A1 1936/4885RAB9A 4108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.