Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967548 | 0.86 | MAPT (0.41) | SLC6A4SLC6A3KMT2AMEN1 | |
| SCHEMBL7455420 | 0.71 | ACHE (0.37) | SLC6A3OPRM1OPRL1ACHEATM | |
| SCHEMBL9114805 | 0.70 | KDM4E (0.40) | OPRM1OPRL1P2RX7CA12CA1 | |
| SCHEMBL6793677 | 0.69 | KIF11 (0.37) | SLC6A4OPRM1OPRL1KMT2AATM | |
| SCHEMBL7229672 | 0.68 | SIGMAR1 (0.38) | SLC6A4OPRM1OPRL1KMT2AMEN1 | |
| SCHEMBL7118273 | 0.68 | ACHE (0.43) | OPRM1OPRL1ACHECA12CA1 | |
| SCHEMBL4451118 | 0.66 | ACHE (0.39) | SLC6A4SLC6A3OPRM1OPRL1ACHE | |
| SCHEMBL5878004 | 0.66 | GAA (0.37) | MAOBSLC6A4SLC6A3MAOA | |
| SCHEMBL5876607 | 0.63 | ALPL (0.34) | KMT2AMEN1POLB | |
| SCHEMBL5876108 | 0.62 | POLB (0.43) | MAOBSLC6A4SLC6A3MAOAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977788-B1 | POLYMERIZABLE COMPOSITIONS BASED ON DIFUNCTIONAL MONOMERS, RESINS AND OPHTHALMIC ARTICLES CONTAINING SAME | CORNING SA (FR) | 2003-07-09 | — | — | EP | disclosed |