Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | BCHE | P06276 | 6/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7728093 | 0.99 | ACHE (0.39) | ACHEBCHEITGA4ITGB7ITGB1 | |
| SCHEMBL7118273 | 0.93 | ACHE (0.43) | ACHEBCHEOPRM1OPRD1OPRK1 | |
| SCHEMBL7455420 | 0.76 | ACHE (0.37) | ACHEBCHEOPRM1OPRL1ALDH1A1 | |
| SCHEMBL8133774 | 0.76 | PRCP (0.34) | KMT2A | |
| SCHEMBL9391964 | 0.75 | ACHE (0.38) | ACHEBCHEALDH1A1LMNA | |
| SCHEMBL7729865 | 0.74 | SLC6A2 (0.33) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6788081 | 0.71 | DRD2 (0.31) | GAA | |
| SCHEMBL7844950 | 0.71 | KDM4E (0.36) | ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7839463 | 0.71 | L3MBTL1 (0.38) | ACHELMNAKMT2AHCRTR1HCRTR2 | |
| SCHEMBL7229672 | 0.68 | SIGMAR1 (0.38) | OPRM1OPRL1ALDH1A1KMT2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170218132-A1 | METHOD OF MAKING PLASTIC ARTICLE | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2017-08-03 | — | — | US | disclosed |
| EP-3174918-A1 | METHOD OF MAKING PLASTIC ARTICLE | SABIC Global Technologies B.V. (NL) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016808-A1 | METHOD OF MAKING PLASTIC ARTICLE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-02-04 | — | — | WO | disclosed |
| EP-2025701-A2 | Polycarbonate articles with photochromic properties | GENERAL ELECTRIC COMPANY (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-0934968-B1 | Polycarbonate articles with photochromic properties | SABIC INNOVATIVE PLASTICS IP (NL) | 2009-01-07 | — | — | EP | disclosed |
| US-7048997-B2 | Production of optical elements | VISION-EASE LENS (US) | 2006-05-23 | — | — | US | disclosed |
| US-6337409-B1 | 3,3-DISUBSTITUTED NAPHTHOPYRAN; COLOR RESPONSE UPON ULTRAVIOLET LIGHT EXPOSURE EXTENDS TO ORANGE, REDDISH-ORANGE OR PURPLE; BATHYCHROMIC SHIFT OF MAXIMUM ACTIVATED WAVELENGTH; PLASTIC OPHTHALMIC LENSES | VISION-EASE LENS, INC. | 2002-01-08 | — | — | US | disclosed |
| US-20010035935-A1 | Production of optical elements | VISION-EASE LENS, INC. | 2001-11-01 | — | — | US | disclosed |
| US-6114437-A | SOLVENT CASTING POLYCARBONATE RESINS PREVIOUSLY HOMOGENEOUSLY MIXED WITH A PHOTOCHROMIC DYE AND THEN EVAPORATING THE SOLVENT; MOLDING MATERIALS; INJECTION MOLDING AT MODERATE TEMPERATURES TO PREVENT DEGRADATION; GLAZINGS | GENERAL ELECTRIC COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| US-6113812-A | BENZOPYRAN COMPOUND | VISION-EASE LENS, INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0934968-A2 | Polycarbonate articles with photochromic properties | GENERAL ELECTRIC COMPANY (US) | 1999-08-11 | — | — | EP | disclosed |
| US-5757459-A | Multifocal optical elements | VISION-EASE LENS, INC. (US) | 1998-05-26 | — | — | US | disclosed |