Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.34 |
| ▸ | MMP13 | P45452 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7118273 | 0.70 | ACHE (0.43) | ALDH1A1L3MBTL1OPRM1OPRL1 | |
| SCHEMBL7021746 | 0.68 | MAOB (0.33) | SLC6A4MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL4451118 | 0.68 | ACHE (0.39) | SLC6A4MEN1KMT2AALDH1A1OPRM1 | |
| SCHEMBL7455420 | 0.67 | ACHE (0.37) | ALDH1A1L3MBTL1OPRM1OPRL1 | |
| SCHEMBL9114805 | 0.66 | KDM4E (0.40) | MEN1KMT2AALDH1A1L3MBTL1OPRM1 | |
| SCHEMBL6793677 | 0.65 | KIF11 (0.37) | SLC6A4KMT2AL3MBTL1OPRM1OPRL1 | |
| Ammonia Solution, Strong SCHEMBL5305768 | 0.65 | ALDH1A1 (0.58) | SIGMAR1SLC6A4PPARGPPARAMEN1 | |
| SCHEMBL4603238 | 0.63 | MEN1 (0.59) | SIGMAR1SLC6A4PPARGPPARAMEN1 | |
| SCHEMBL4603241 | 0.63 | MEN1 (0.59) | SIGMAR1SLC6A4PPARGPPARAMEN1 | |
| SCHEMBL6788081 | 0.63 | DRD2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627121-B1 | Plastic lenses; high optical density on photoactivation; high fatigue resistance; fast decoloration in dark | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2003-09-30 | — | — | US | disclosed |