Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.48 |
| ▸ | MAOB | P27338 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538212 | 0.88 | PTPN1 (0.49) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL365385 | 0.87 | MAOA (0.58) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Ethane SCHEMBL27840767 | 0.83 | MAOA (0.55) | MAOAMAOBALDH1A1KDM4EHPGD | |
| Benzene SCHEMBL27821367 | 0.83 | ACHE (0.58) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL28230155 | 0.72 | FTO (0.63) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL29597364 | 0.71 | SIRT2 (0.46) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL21858235 | 0.71 | ALDH1A1 (0.38) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL9432877 | 0.70 | FTO (0.55) | MAOAMAOBKDM4EFTOACHE | |
| SCHEMBL1256888 | 0.68 | AHR (0.41) | MAOAMAOBALDH1A1KDM4EHPGD | |
| SCHEMBL24046753 | 0.68 | ALOX15 (0.45) | MAOAMAOBALDH1A1HPGDGABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322308-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | Durect Corporation (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002028366-A9 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORP (US) | 2003-02-13 | — | — | WO | disclosed |
| WO-2002028366-A2 | DEVICES AND METHODS FOR MANAGEMENT OF INFLAMMATION | DURECT CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |