Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021515 | 0.85 | POLB (0.53) | MEN1ALDH1A1KMT2ANPC1MAPT | |
| SCHEMBL7028010 | 0.80 | MEN1 (0.60) | CASRCNR2L3MBTL1MEN1ALDH1A1 | |
| SCHEMBL7024089 | 0.79 | SMN1; SMN2 (0.51) | CASRALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2091346 | 0.75 | LMNA (0.47) | CHRNB2CHRNB4CHRNA3CHRNA4L3MBTL1 | |
| SCHEMBL7030624 | 0.73 | POLB (0.56) | MEN1ALDH1A1KMT2ANPC1MAPT | |
| SCHEMBL7028473 | 0.73 | HTR2A (0.43) | CASRDPP7HDAC3HDAC1HDAC2 | |
| SCHEMBL491229 | 0.72 | RAB9A (0.54) | CHRNB2CHRNB4CHRNA3CHRNA4L3MBTL1 | |
| SCHEMBL15966571 | 0.70 | TSHR (0.42) | DPP7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL15966536 | 0.70 | TSHR (0.42) | DPP7CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL11664172 | 0.68 | HDAC1 (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032834-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-13 | — | — | US | disclosed |
| EP-1257528-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001060786-A1 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032834-A1 | Aminoalcohol derivatives | ADRB1, ADRB2, ADRB3 | CASR 1433/4885DPP7 3708/4885CHRNB2 167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.