Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | USP18 | Q9UMW8 | 1/20 | 0.33 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3091631 | 0.66 | GLA (0.61) | MEN1KMT2AHSD17B10ACHEPOLB | |
| SCHEMBL424558 | 0.65 | ALDH1A1 (0.54) | HSD17B10ACHEALDH1A1RECQLLMNA | |
| SCHEMBL14292215 | 0.65 | MEN1 (0.48) | MEN1KMT2AHSD17B10ACHEPOLB | |
| SCHEMBL18039684 | 0.65 | BACE1 (0.61) | ALDH1A1LMNAMAPK1MAPTCES1 | |
| SCHEMBL679340 | 0.65 | LOXL2 (0.46) | MEN1KMT2AHSD17B10ACHEPOLB | |
| SCHEMBL3093347 | 0.65 | ALDH1A1 (0.59) | MEN1KMT2APOLBALDH1A1LMNA | |
| SCHEMBL27909482 | 0.64 | ALDH1A1 (0.72) | MEN1KMT2AHSD17B10ACHEALDH1A1 | |
| SCHEMBL22567 | 0.64 | ALDH1A1 (0.72) | MEN1KMT2AHSD17B10ACHEALDH1A1 | |
| SCHEMBL8247259 | 0.64 | TSHR (0.46) | KMT2ACYP1A2CYP2C19CA12CA9 | |
| Hydrochloric Acid SCHEMBL11060473 | 0.63 | ALDH1A1 (0.52) | HSD17B10ACHEPOLBALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742139-B2 | No-carrier-added nucleophilic [F-18] fluorination of aromatic compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-06-03 | — | — | US | disclosed |
| US-20120123120-A1 | No-Carrier-Added Nucleophilic [F-18] Fluorination of Aromatic Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120123120-A1 | No-Carrier-Added Nucleophilic [F-18] Fluorination of Aromatic Compounds | SLC18A1, SLC18A2, SLC6A2 | MEN1 1959/4885KMT2A 1113/4885HSD17B10 733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.