Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023287 | 0.99 | MMP2 (0.37) | MMP2MMP9HSD11B1HSD11B2CNR1 | |
| SCHEMBL7026787 | 0.91 | HSD11B1 (0.38) | HSD11B1HSD11B2CNR1CNR2STS | |
| SCHEMBL7023911 | 0.89 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL7021356 | 0.89 | HSD11B1 (0.37) | MMP2MMP9HSD11B1HSD11B2CNR1 | |
| SCHEMBL7021338 | 0.89 | HSD11B1 (0.37) | MMP2MMP9HSD11B1HSD11B2CNR1 | |
| SCHEMBL7016925 | 0.81 | HSD11B1 (0.35) | MMP2MMP9HSD11B1HSD11B2CNR1 | |
| SCHEMBL7023103 | 0.80 | RAB9A (0.35) | MMP2MMP9HSD11B1HSD11B2CNR1 | |
| SCHEMBL7026052 | 0.79 | PNMT (0.31) | — | |
| SCHEMBL7019483 | 0.78 | ESR1 (0.41) | HSD11B1HSD11B2CNR1CNR2 | |
| SCHEMBL7025606 | 0.78 | PGR (0.42) | HSD11B1HSD11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0929509-B1 | LIQUID CRYSTAL ALKENYL BICYCLO 2.2.2]OCTANES AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | QINETIQ LTD (GB) | 2003-01-15 | — | — | EP | disclosed |
| US-6187393-B1 | FOR LIQUID CRYSTAL DISPLAYS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 2001-02-13 | — | — | US | disclosed |