SCHEMBL7028778

SCHEMBL7028778

Cc1ccc(S(=O)(=O)OS(c2ccc(C(C)(C)C)cc2)(c2ccc(C(C)(C)C)cc2)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.53
ACHE P22303 1/20 0.53
TSHR P16473 1/20 0.52
LMNA P02545 4/20 0.48
ALDH1A1 P00352 6/20 0.47
HSD11B1 P28845 2/20 0.46
HSD17B3 P37058 1/20 0.45
HSD17B2 P37059 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 2/20 0.41
RECQL P46063 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
GAA P10253 2/20 0.41
HCRTR2 O43614 1/20 0.40
HTT P42858 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
USP2 O75604 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3140903 0.94 HSD11B1 (0.48) BCHEACHETSHRLMNAALDH1A1
SCHEMBL452980 0.94 HSD11B1 (0.48) BCHEACHETSHRLMNAALDH1A1
SCHEMBL5709666 0.91 MEN1 (0.54) BCHEACHETSHRALDH1A1HSD11B1
SCHEMBL2966008 0.87 GAA (0.52) LMNAALDH1A1MEN1KMT2AMAPT
SCHEMBL5171841 0.86 ALDH1A1 (0.50) BCHEACHELMNAALDH1A1HSD11B1
SCHEMBL2634260 0.86 HSD11B1 (0.53) LMNAALDH1A1HSD11B1HSD17B3HSD17B2
SCHEMBL451539 0.86 HSD11B1 (0.53) LMNAALDH1A1HSD11B1HSD17B3HSD17B2
SCHEMBL7896391 0.83 HSD11B1 (0.50) LMNAALDH1A1HSD11B1HSD17B3MEN1
SCHEMBL27872565 0.83 ALDH1A1 (0.59) BCHEACHETSHRLMNAALDH1A1
SCHEMBL6741010 0.83 HSD11B1 (0.45) BCHEACHETSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576401-B2 Free radical polymerizable acrylic unsaturated monomer, an infrared absorbing dye ROHM AND HAAS ELECTRONIC MATERIALS LLC 2003-06-10 US disclosed
US-20030082475-A1 Thermosensitive layer on substrate; free radical generator ROHM AND HAAS ELECTRONIC MATERIALS LLC 2003-05-01 US disclosed