SCHEMBL7029545

SCHEMBL7029545

Cc1ccc(NC(=O)N[C@@H](CNC(=O)c2ccc(OCCNC(=N)N)cc2O)C(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 3/20 0.44
F2 P00734 2/20 0.44
F10 P00742 2/20 0.44
PLAT P00750 2/20 0.44
KMT2A Q03164 4/20 0.44
POLB P06746 4/20 0.44
MEN1 O00255 3/20 0.44
PLG P00747 3/20 0.40
KLKB1 P03952 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALPL P05186 1/20 0.37
ALPI P09923 1/20 0.37
ALPG P10696 1/20 0.37
NPC1 O15118 1/20 0.37
FPR2 P25090 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7038403 0.93 FPR2 (0.45) PLAUF2F10PLATPOLB
SCHEMBL7036018 0.92 F10 (0.42) PLAUF2F10PLATKMT2A
SCHEMBL7037397 0.92 F10 (0.47) PLAUF2F10PLATPOLB
SCHEMBL7032270 0.92 PLAU (0.42) PLAUF2F10PLATKMT2A
SCHEMBL7029540 0.92 PLAU (0.42) PLAUF2F10PLATPOLB
SCHEMBL7030513 0.89 FPR2 (0.47) PLAUF2F10PLATKMT2A
SCHEMBL7032350 0.89 MEN1 (0.46) PLAUF2F10PLATKMT2A
SCHEMBL7251419 0.87 MEN1 (0.42) PLAUF2F10PLATKMT2A
SCHEMBL7038269 0.87 PYGL (0.41) PLAUF2F10PLATKMT2A
SCHEMBL7255333 0.86 F10 (0.40) PLAUF2F10PLATKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR PLAU 2202/4885F2 4014/4885F10 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.