SCHEMBL7037397

SCHEMBL7037397

CC(=O)c1ccc(NC(=O)N[C@@H](CNC(=O)c2ccc(OCCNC(=N)N)cc2O)C(=O)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
F10 P00742 5/20 0.47
PLAU P00749 3/20 0.47
F2 P00734 3/20 0.47
PLAT P00750 2/20 0.47
KLKB1 P03952 2/20 0.38
POLB P06746 1/20 0.37
PLG P00747 2/20 0.37
GAA P10253 1/20 0.36
MCHR1 Q99705 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TAOK1 Q7L7X3 1/20 0.36
TAOK3 Q9H2K8 1/20 0.36
FOLH1 Q04609 4/20 0.36
F7 P08709 3/20 0.36
FPR2 P25090 1/20 0.36
F3 P13726 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7038403 0.92 FPR2 (0.45) F10PLAUF2PLATKLKB1
SCHEMBL7029545 0.92 PLAU (0.44) F10PLAUF2PLATKLKB1
SCHEMBL7036018 0.91 F10 (0.42) F10PLAUF2PLATKLKB1
SCHEMBL7032270 0.90 PLAU (0.42) F10PLAUF2PLATKLKB1
SCHEMBL7029540 0.90 PLAU (0.42) F10PLAUF2PLATKLKB1
SCHEMBL7030513 0.88 FPR2 (0.47) F10PLAUF2PLATKLKB1
SCHEMBL7032315 0.85 PLAU (0.38) F10PLAUF2PLATKLKB1
SCHEMBL7255333 0.84 F10 (0.40) F10PLAUF2PLATKLKB1
SCHEMBL7251419 0.84 MEN1 (0.42) F10PLAUF2PLATKLKB1
SCHEMBL7034864 0.84 CA2 (0.43) F10PLAUF2PLATCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR F10 2695/4885PLAU 2202/4885F2 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.