SCHEMBL7038403

SCHEMBL7038403

COc1ccc(NC(=O)N[C@@H](CNC(=O)c2ccc(OCCNC(=N)N)cc2O)C(=O)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.45
PLAU P00749 3/20 0.44
F2 P00734 3/20 0.44
F10 P00742 3/20 0.44
PLAT P00750 2/20 0.44
KLKB1 P03952 2/20 0.43
POLB P06746 1/20 0.40
ANPEP P15144 1/20 0.39
PKM P14618 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PLG P00747 1/20 0.38
F7 P08709 1/20 0.38
F3 P13726 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
FPR1 P21462 2/20 0.37
CASR P41180 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7029545 0.93 PLAU (0.44) FPR2PLAUF2F10PLAT
SCHEMBL7036018 0.92 F10 (0.42) FPR2PLAUF2F10PLAT
SCHEMBL7037397 0.92 F10 (0.47) FPR2PLAUF2F10PLAT
SCHEMBL7029540 0.92 PLAU (0.42) FPR2PLAUF2F10PLAT
SCHEMBL7032270 0.92 PLAU (0.42) PLAUF2F10PLATKLKB1
SCHEMBL7030513 0.89 FPR2 (0.47) FPR2PLAUF2F10PLAT
SCHEMBL7034864 0.89 CA2 (0.43) PLAUF2F10PLATALDH1A1
SCHEMBL7034753 0.87 ALDH1A1 (0.43) POLBANPEPPKMALDH1A1
SCHEMBL7030722 0.87 F10 (0.40) PLAUF2F10PLATKLKB1
SCHEMBL7255333 0.86 F10 (0.40) PLAUF2F10PLATKLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR FPR2 412/4885PLAU 2202/4885F2 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.