SCHEMBL1607997

SCHEMBL1607997

O=[N+]([O-])c1ccc2ocnc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
RAB9A P51151 6/20 0.48
NPC1 O15118 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
TXNRD1 Q16881 1/20 0.47
TXNRD3 Q86VQ6 1/20 0.47
TXNRD2 Q9NNW7 1/20 0.47
MAPT P10636 4/20 0.46
MCL1 Q07820 1/20 0.46
ATM Q13315 1/20 0.46
GAA P10253 1/20 0.45
CYP3A4 P08684 1/20 0.45
NAMPT P43490 1/20 0.45
XDH P47989 1/20 0.45
DYRK1A Q13627 1/20 0.42
CYP1A2 P05177 1/20 0.42
GPR35 Q9HC97 2/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580246 1.00 ALDH1A1 (0.49) ALDH1A1MEN1KMT2ARAB9ANPC1
Hydrazine SCHEMBL27557478 0.97 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL29216330 0.87 RAB9A (0.54) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL7029620 0.86 CYP3A4 (0.49) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL1191939 0.79 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL29887958 0.79 ALDH1A1 (0.46) ALDH1A1MEN1KMT2ARAB9ANPC1
SCHEMBL20741518 0.78 F7 (0.48) ALDH1A1MEN1KMT2ATXNRD1TXNRD3
SCHEMBL31700862 0.78 HSPD1 (0.61) ALDH1A1MEN1KMT2AMAPTCYP3A4
Nitrobenzene SCHEMBL28594946 0.76 LMNA (0.53) ALDH1A1MEN1KMT2ARAB9ANPC1
Nitrobenzene SCHEMBL28018227 0.76 LMNA (0.53) ALDH1A1MEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117926287-A Method for synthesizing 2-aminobenzoxazole derivative under electrochemical condition 湘潭大学 2024-04-26 CN claimed
CN-117736159-A Preparation method of chlorzoxazone 九江善水科技股份有限公司 2024-03-22 CN claimed
US-7091360-B2 Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof AVENTIS PHARMA S.A. (US) 2006-08-15 US claimed
EP-1495007-A4 PROCESS FOR PREPARING HETEROARYL AND UNSATURATED HETEROCYCLOALKYLMAGNESIUM REAGENTS AND USES AXYS PHARM INC (US) 2006-05-03 EP claimed
EP-1495007-A1 PROCESS FOR PREPARING HETEROARYL AND UNSATURATED HETEROCYCLOALKYLMAGNESIUM REAGENTS AND USES AXYS PHARMACEUTICALS, INC. (US) 2005-01-12 EP claimed
US-20040019218-A1 Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof AXYS PHARMACEUTICALS, INC. 2004-01-29 US claimed
WO-2003087068-A1 PROCESS FOR PREPARING HETEROARYL AND UNSATURATED HETEROCYCLOALKYLMAGNESIUM REAGENTS AND USES AXYS PHARMACEUTICALS, INC. (US) 2003-10-23 WO claimed
EP-0278509-B1 Silver halide photographic emulsion FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP claimed
US-4970141-A ELEVATED SPECTRAL SENSITIVITY IN GREEN WAVELENGTH REGION FUJI PHOTO FILM CO., LTD. (JP) 1990-11-13 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
EP-0278509-A2 Silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1988-08-17 EP claimed
WO-2025137541-A1 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2025-06-26 WO disclosed
EP-4539840-A1 KINASE MODULATORS AND METHODS OF USE THEREOF Neuron23, Inc. (US) 2025-04-23 EP disclosed
US-20250002511-A1 AKT3 MODULATORS Georgiamune Inc. 2025-01-02 US disclosed
WO-2023244788-A9 KINASE MODULATORS AND METHODS OF USE THEREOF NEURON23, INC. (US) 2024-09-12 WO disclosed
US-3988154-A Photographic supports and elements utilizing photobleachable omicron-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3988156-A Photographic supports and elements utilizing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-26 US disclosed
US-3984248-A Photographic polymeric film supports containing photobleachable o-nitroarylidene dyes EASTMAN KODAK COMPANY (US) 1976-10-05 US disclosed
US-3955996-A Method for spectrally sensitizing photographic light-sensitive emulsion FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US disclosed
US-3945832-A Fogged, direct-positive silver halide emulsion containing desensitizers and a dimethine optical sensitizing dye FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040019218-A1 Process for preparing heteroaryl and unsaturated heterocycloalkylmagnesium reagents and uses thereof SPINT2, CTSV, CTSZ ALDH1A1 2466/4885MEN1 979/4885KMT2A 2891/4885
US-20250002511-A1 AKT3 MODULATORS AKT3, PIK3C2A, PIK3C2B ALDH1A1 4131/4885MEN1 3769/4885KMT2A 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.