Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034657 | 0.98 | PTGS2 (0.36) | PTGS2CYP11B2CYP11B1MTNR1AMTNR1B | |
| SCHEMBL6907784 | 0.80 | PTGS2 (0.37) | PTGS2CYP11B2CYP11B1MTNR1AMTNR1B | |
| SCHEMBL7423243 | 0.79 | PTGS2 (0.41) | PTGS2CYP11B2CYP11B1MTNR1AMTNR1B | |
| SCHEMBL5179240 | 0.73 | CYP11B2 (0.34) | PTGS2CYP11B2CYP11B1MTNR1AMTNR1B | |
| SCHEMBL7202063 | 0.73 | PTGS2 (0.35) | PTGS2CYP11B2CYP11B1MAOAMAOB | |
| SCHEMBL6908479 | 0.72 | PTGS2 (0.33) | PTGS2CYP11B2CYP11B1ACHE | |
| Hydrochloric Acid SCHEMBL6764889 | 0.71 | CYP11B2 (0.33) | PTGS2CYP11B2CYP11B1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL5188847 | 0.71 | CYP11B2 (0.36) | PTGS2CYP11B2CYP11B1MTNR1AMTNR1B | |
| SCHEMBL8031056 | 0.69 | PTGS2 (0.53) | PTGS2CYP11B2CYP11B1MTNR1AMTNR1B | |
| SCHEMBL7196319 | 0.69 | ACHE (0.35) | PTGS2CYP11B2CYP11B1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6646071-B1 | Catalysts for high temperature solution polymerization | THE DOW CHEMICAL COMPANY | 2003-11-11 | — | — | US | disclosed |
| EP-1178996-B1 | METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1178996-A1 | METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS | THE DOW CHEMICAL COMPANY (US) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069870-A1 | METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS | THE DOW CHEMICAL COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |