Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423243 | 0.77 | PTGS2 (0.41) | ACHEPTGS2CYP11B2CYP11B1 | |
| SCHEMBL6907784 | 0.72 | PTGS2 (0.37) | ACHEPTGS2CYP11B2CYP11B1 | |
| SCHEMBL19816425 | 0.71 | RAB9A (0.38) | — | |
| SCHEMBL7034657 | 0.70 | PTGS2 (0.36) | ACHEPTGS2CYP11B2CYP11B1 | |
| SCHEMBL7031079 | 0.69 | PTGS2 (0.35) | ACHEPTGS2CYP11B2CYP11B1 | |
| SCHEMBL8031056 | 0.68 | PTGS2 (0.53) | ACHEPTGS2CYP11B2CYP11B1 | |
| SCHEMBL7193903 | 0.68 | HTR1D (0.30) | — | |
| SCHEMBL7193898 | 0.68 | ADRA2A (0.30) | — | |
| Hydrochloric Acid SCHEMBL6906839 | 0.66 | — | — | |
| SCHEMBL6908479 | 0.66 | PTGS2 (0.33) | ACHEPTGS2CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880534-B1 | HETEROATOM SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS AND METHODS FOR PREPARING THEM | BOREALIS TECH OY (FI) | 2003-12-17 | — | — | EP | disclosed |
| US-6277778-B1 | COORDINATION CATALYSTS | BOREALIS A/S (DK) | 2001-08-21 | — | — | US | disclosed |
| EP-0880534-A1 | HETEROATOM SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS AND METHODS FOR PREPARING THEM | BOREALIS A/S (DK) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028170-A1 | HETEROATOM SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS AND METHODS FOR PREPARING THEM | BOREALIS A/S (DK) | 1997-08-07 | — | — | WO | disclosed |