Potassium Ion

Potassium Ion

SCHEMBL7032417

CCCC[O-].CCCC[O-].CCCC[O-].CCCC[O-].[Al+3].[K+]

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.43
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.40
CES1 P23141 6/20 0.35
CES2 O00748 5/20 0.35
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC22A1 O15245 2/20 0.32
SLC22A2 O15244 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LSS P48449 1/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL3888413 0.96 TSHR (0.46) TSHRLMNATHRBCES1CES2
Potassium Ion SCHEMBL37894 0.96
SCHEMBL28510902 0.96 TSHR (0.46) TSHRLMNATHRBCES1CES2
SCHEMBL28907 0.96 TSHR (0.46) TSHRLMNATHRBCES1CES2
Potassium Ion SCHEMBL31202579 0.96 TSHR (0.46) TSHRLMNATHRBCES1CES2
Potassium Ion SCHEMBL17113317 0.96 TSHR (0.46) TSHRLMNATHRBCES1CES2
Potassium Ion SCHEMBL25313540 0.92 TSHR (0.43) TSHRLMNATHRBCES1CES2
SCHEMBL1230320 0.92 TSHR (0.43) TSHRLMNATHRBCES1CES2
SCHEMBL1229359 0.92 TSHR (0.43) TSHRLMNATHRBCES1CES2
SCHEMBL1228550 0.92 TSHR (0.43) TSHRLMNATHRBCES1CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1290102-A1 THE USE OF STAR-BRANCHED POLYMERS IN PRESSURE SENSITIVE ADHESIVES National Starch and Chemical Investment Holding Corporation (US) 2003-03-12 EP disclosed
WO-2001094490-A1 THE USE OF STAR-BRANCHED POLYMERS IN PRESSURE SENSITIVE ADHESIVES NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2001-12-13 WO disclosed
US-6177540-B1 MERCAPTAN CORE AND THREE OR MORE POLYMER SEGMENTS WHICH EXTEND RADIALLY FROM THE MERCAPTAN CORE INCLUDING CARBOXYLIC ACID MOIETIES NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2001-01-23 US disclosed
US-5068291-A Method of preparing pressure sensitive adhesives with accelerated cure rate NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1991-11-26 US disclosed
US-4292231-A CARBOXY AND CARBAMATE-FUNCTIONAL VINYL INTERPOLYMER ASHLAND OIL, INC. (US) 1981-09-29 US disclosed
US-4005247-A ACRYLATE INTERPOLYMER, METAL ALKOXIDE ASHLAND OIL, INC. (US) 1977-01-25 US disclosed