Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 1.00 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | TAS1R2 | Q8TE23 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703277 | 1.00 | TAS1R3 (1.00) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL2406255 | 0.85 | HTT (1.00) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL5436807 | 0.85 | HTT (1.00) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL5909488 | 0.85 | TAS1R3 (0.73) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL5909489 | 0.85 | TAS1R3 (0.73) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL6572555 | 0.84 | LMNA (0.82) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL21780113 | 0.84 | HTT (0.82) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL10527008 | 0.83 | HTT (0.80) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL22289415 | 0.83 | HTT (0.84) | TAS1R3TAS1R1HTTLMNAKMT2A | |
| SCHEMBL30823638 | 0.83 | HTT (0.84) | TAS1R3TAS1R1HTTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | SENOMYX, INC. | 2020-02-13 | — | — | US | disclosed |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2020-02-11 | — | — | US | disclosed |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | SENOMYX, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| EP-1659881-B1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC (US) | 2019-04-03 | — | — | EP | disclosed |
| EP-3431464-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| US-20180364220-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED | 2018-12-20 | — | — | US | disclosed |
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| US-20180003702-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | SENOMYX, INC. | 2018-01-04 | — | — | US | disclosed |
| US-20150093339-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED | 2015-04-02 | — | — | US | disclosed |
| US-8735081-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | SENOMYX, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-8404455-B2 | Chimeric T1R taste receptor polypeptides and nucleic acid sequences encoding and cell lines that express said chimeric T1R polypeptides | SENOMYX, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20130030059-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | FIRMENICH INCORPORATED | 2013-01-31 | — | — | US | disclosed |
| US-8124121-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110294981-A1 | CHIMERIC T1R TASTE RECEPTOR POLYPEPTIDES AND NUCLEIC ACID SEQUENCES ENCODING AND CELL LINES THAT EXPRESS SAID CHIMERIC T1R POLYPEPTIDES | FIRMENICH INCORPORATED | 2011-12-01 | — | — | US | disclosed |
| US-7888470-B2 | Chimeric T1R taste receptor polypeptides and nucleic acid sequences encoding and cell lines that express said chimeric T1R polypeptides | SENOMYX, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX, INC. | 2009-04-30 | — | — | US | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | SENOMYX, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | FIRMENICH INCORPORATED | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | TAS1R3 5/4885TAS1R1 2/4885HTT 411/4885 |
| US-20110294981-A1 | CHIMERIC T1R TASTE RECEPTOR POLYPEPTIDES AND NUCLEIC ACID SEQUENCES ENCODING AND CELL LINES THAT EXPRESS SAID CHIMERIC T1R POLYPEPTIDES | TAS1R1, TAS1R2, TAS1R3 | TAS1R3 3/4885TAS1R1 1/4885HTT 718/4885 |
| US-20150093339-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TAS1R3 5/4885TAS1R1 2/4885HTT 509/4885 |
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885HTT 632/4885 |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | TAS1R3 5/4885TAS1R1 2/4885HTT 411/4885 |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885HTT 632/4885 |
| US-20180003702-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885HTT 632/4885 |
| US-20180364220-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TAS1R3 5/4885TAS1R1 2/4885HTT 509/4885 |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TAS1R3 5/4885TAS1R1 2/4885HTT 509/4885 |
| US-20130030059-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | TAS1R1, TAS1R2, TAS2R1 | TAS1R3 4/4885TAS1R1 1/4885HTT 640/4885 |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | TAS2R40, TAS2R4, TAS2R30 | TAS1R3 17/4885TAS1R1 11/4885HTT 699/4885 |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | TAS1R3, TAS1R2, TAS2R30 | TAS1R3 1/4885TAS1R1 4/4885HTT 1544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.